Stimulation of the breakdown and resynthesis of of phosphatidylinositol in rat hepatocytes by angiotensin, vasopressin and adrenaline.
نویسندگان
چکیده
Ginsburg, M. (1968) Hundb. Exp. Phartnacol. 23, 286-371 Hems, D. A., Rodrigues, L. M. & Whitton, P. D. (1978) Biochem. J. 172, 311-317 Kai, M. & Hawthorne, J. N. (1966) Biochetn. J . 98, 62-67 Keppens, S., Vandenheede, J. R. & De Wulf, H. (1977) Biochinz. Biophys. Acra 496,448-457 Kirk, C . J. & Hems, D. A. (1974) FEBS Letr. 47, 128-131 Kirk, C. J., Verrinder, T. R. & Hems, D. A. (1977) FEBS Lett. 83, 267-271 Krebs, H. A. & Henseleit, K. (1932) Hoppe-Seyler’s 2. Physiol. Chetn. 210, 33-66 Michell, R. H. (1975) Biochitn. Biophys. Actn 415, 81-147 Michell, R. H., Jafferji, S. S. & Jones, L. M. (1977) in Function and Biosynrhesis ofLipids (Bazan, N. G., Brenner, R. R. & Giusto, N. M., eds.), pp. 447-464, Plenum Press, New York Sherline, P., Lynch, A. & Glinsrnann, W. H. (1972) Endocrinology 91,680-690 Van De Werve, G., Hue, L. & Hers, H. G. (1977) Biochem. J. 162, 135-142 2662-2669
منابع مشابه
Phosphatidylinositol metabolism in rat hepatocytes stimulated by glycogenolytic hormones. Effects of angiotensin, vasopressin, adrenaline, ionophore A23187 and calcium-ion deprivation.
1. The effects on phosphatidylinositol metabolism of three Ca(2+)-mobilizing glycogenolytic hormones, namely angiotensin, vasopressin and adrenaline, have been investigated by using rat hepatocytes. 2. All three hormones stimulate both phosphatidylinositol breakdown and the labelling of this lipid with (32)P. 3. The response to angiotensin occurs quickly, requires a high concentration of the ho...
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Vasopressin stimulated a 40% decrease in [32P]phosphatidylinositol 4,5-bisphosphate and a 15% decrease in [32P]phosphatidylinositol within 30 s of addition to hepatocytes prelabeled for 60 min with 32P. In hepatocytes prelabeled with [3H]inositol for 60 min, vasopressin produced 20% breakdown of phosphatidylinositol and 33% breakdown of phosphatidylinositol 4,5-bisphosphate within 30 s. There w...
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 6 5 شماره
صفحات -
تاریخ انتشار 1978